Sunday, May 24, 2020
Wednesday, May 13, 2020
Early Childhood Development Lakeland Little Learners
Lakeland Little Learners Early childhood development is one of the most important aspects to the human life. Early childhood is mainly referred to from the time of birth through age five. Although, children learn based on the influence of their familiar environment, every child is expected to develop in their own unique way. Lakeland Little Learners is an educational program that provides an excellent environment for ensuring that every childââ¬â¢s social, cognitive, physical and educational needs are met. LLL provides a very welcoming and caring atmosphere for children from ages two weeks to twelve years old. During my experience at LLL, I was able to sit and observe three classrooms with very different age groups of children. Uponâ⬠¦show more contentâ⬠¦While sitting and observing circle time I noticed that the children were very directed. They all sat quietly and listened to the teacher. Before speaking they knew to raise their hands and they were called upon before spea king. If perhaps a student spoke without being called on they were redirected as they coped with that very well. After starting with the 4K program, I then went to the late threeââ¬â¢s room. In the late threeââ¬â¢s room, I noticed a lot of the same activities going on however the behavior was much different. The arriving schedule was very similar for both three and four year olds. Just as the 4K room the kids arrived and began the day with circle time following hanging their coats and washing hands. One of the differences I noticed during circle time was the attention span was much shorter with the three year olds. Many of the kids where getting up often and wandering off to different play areas, pushing one another, and interrupting when the teacher was talking. Once they were redirected there was some crying and attitude unlike the four year olds who took direction fairly well. Once disciplined I noticed that the child would wander off and sit by him/her self. Some differenc es I noticed in the learning activities where: the threes focused only on the first letter of
Wednesday, May 6, 2020
Blood Transfusion Free Essays
BIOPURE INDUSTRIESA Marketing Analysis Based on the data from the case study by Jonn Gourville, Biopure Corporation , HBS, 1998April 20, 2005By Veronica Stepanova Executiveà Summaryâ⬠¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦ 2 Situation AnalysisI. Humanà Marketâ⬠¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦.. We will write a custom essay sample on Blood Transfusion or any similar topic only for you Order Now 3II. Animalà Marketâ⬠¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦.. 5 Marketing Planà for oxyglobinâ⬠¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦. 6 Finalà decisionâ⬠¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦ 7 Appendix 1 A (Excel documents, separate attachment) Appendix 1 B Executive Summary Many opportunities are available in the human blood market due to several disadvantages of thecurrently available alternatives. Even more opportunities exist in theà animal blood market. â⬠¢Oxyglobin should be positioned as a high-quality product designed for middle- to upper-classbudgets. â⬠¢The price for Oxyglobin should be about $200 for the consumer and around $100 for the supplier(animal hospital) to account for distribution markups and otherà carrying costs. â⬠¢Distribution should be oriented in the regionalà vicinity of the operation and implement largerclinics. In addition, only emergency clinics are to be targeted. Current opportunities are favorable for Oxyglobinââ¬â¢s launch. Situation Analysis I. Human blood market. â⬠¢Patients with acute blood loss fromà traumaà and surgery ââ¬â 40% individuals aged 65+. â⬠¢Chronic anemiaà patients (any age) ââ¬â 1. 5 million for the year 1995. â⬠¢Blood loss, resulting from trauma (e. g. car accident) and exceeding 2-3 units (1 unit = 10% ofà total blood content of human body) needs immediateà blood transfusion. â⬠¢Price is largely cost-based (storage, implementation) ââ¬â blood donation is free. Existing options. â⬠¢Redà blood cellsà and their components (hemoglobin, platelets, and plasma) areà collected viadonations, organized by blood collection centers andà then transfused into patients. â⬠¢Current options allow for storage for 6à weeks in refrigerated conditions, consequently disposed ofà if unused. Hemoglobin uses oxygen-carrying efficiency by 50% if not usedà within the first few weeks. â⬠¢Blood transfusion is subject to blood typing (A, B,à AB, O, positive, negative) andreception/rejection by the body. Incorrect matching may be fatalà for the patient. Infection risks slow down the process ofà testing blood prior to its use and areà greater if blood isnot separated into components. Infections include the risks of AIDS, hepatitis B,à and contamination. â⬠¢Blood transfusion is available on-site only (hospital or emergency room); as aà result, 30% traumapatients die prior to operation. â⬠¢Blood supply is lower than demand, esp ecially during peak periods (summerà months and winterholidays, during which car and other travel increases ? fewer donors and more patients). Blood substitutes. â⬠¢3 companies in final stages awaiting FDAà approval (clinical testing). Entrance into market is difficult (all current processes patented) andà time-consuming ââ¬â may takeup to 17 years (See case Exhibit 3). Potential to replace current blood drawing process byà component separation and purification, aswell as chemical modification and stabilization of hemoglobin. Reduced risk of contamination and increased storage capability of 2 years. Added benefits for patients with constricted or restricted blood vessels (smaller size improvedaccessibility to organs). Possibility of adapting animal blood cells for use inà humans. Risk of toxicity and body rejection (sped upà excretion). Competitors/industry players .A. Baxter à Northfield Laboratories. â⬠¢Both rely on human blood supply toà derive hemoglo bin. â⬠¢Red blood cells obtained from expired banks. â⬠¢Require refrigeration. Baxter: â⬠¢Leader in development and manufacturing of blood-oriented medical equipment. â⬠¢Large facility ââ¬â production capacity of 1 million units/year, spent $250à million on RD. â⬠¢Product ââ¬â HemAssist ââ¬â to beà priced between $600-$800. Northfield: â⬠¢Small facility ââ¬âà 10,000-unit production capability but possible expansion intoà 300,000 units/year. Focus on single product (PolyHeme), $70 million spent on development. B. Biopure Corporation. â⬠¢Specializes in protein purification for pharmaceutical use. â⬠¢Hemopure 2 years away from final approval. â⬠¢Derived from the blood of cattle. â⬠¢Production capacity of 150,000 butà possible production limitations due to expected concurrentusage of production equipment for animal version. â⬠¢Need for removal ofà hemoglobin clusters from product? excess process inà production abi lity. â⬠¢Cost for Biopure at $1. 50 per unit of animal blood, but plan to match Baxterââ¬â¢s price for finalconsumer product. II. Animal blood market. â⬠¢Mainly cats (35%) and dogs (50%). â⬠¢800 dogs were brought to emergencyà treatment due to acute blood loss in 1995,à 2. 5% severe. Existing options. â⬠¢15,000 veterinary clinics. â⬠¢5% of vet clinics perform emergency care, with a 75% referral rate from primary careà clinics. â⬠¢Current blood banks insufficient, demand greatly exceeds supply: 2. 5 out of 30à cases treated. â⬠¢93% blood drawn from donor animals (78%à in emergencies) ââ¬â an ethically questionable practice. â⬠¢150 units of blood transfused per emergency care, 17 perà primary care center (Appendix A). No effective blood typing or cross-matching systems. â⬠¢Blood collection, storage, and transfusion too costly for proper operation. â⬠¢Current cost of clinical careà to animal owners relatively high, undesirable. ? 84% doctor dissatisfaction with current alternatives. Blood substitutes. â⬠¢Biopureââ¬â¢s Oxyglobin currently the only exi stingà FDA-approved substitute ready for launch. â⬠¢No evident chemical difference in theà production process between animal and human supplement. â⬠¢Animal supplement approved sooner than human equivalent due to less-strict regulations in theanimal consumer market. Production capacity of 300,000 units, $200 million spent on development (combined withHemopure) Marketing Plan for OxyglobinPositioning strategy. Most animal owners (enthusiasts) can beà assumed to be within the middle toà upperincome class, based on the extraneous costs of owning an animal (refer to case Exhibit 8 for a summary ofà average costs of keeping aà pet). However, many consumers proved to beà price-conscious about spendingadditional funds on optional services (this will be analyzed further in theà pricing strategy); therefore, nopremium strategy should be used. The product should be positioned asà a high-quality supplement forblood transfusion, available to (affordable by) most animal owners. Pricing strategy. As cited, animalà owners expect to spend limited amounts of money onà animal care; thisis slightly different for emergency situations, where customers are willing to spend more,à as demonstratedby the survey results (Exhibit 8; Table B). The typical cost of aà blood transfusion to the customer iscurrently $100 for the traditional method; however, this price wasà said to have been cost-unjustified. Still,veterinarians were cited as theà trusted source for determining a patientââ¬â¢s treatment selection, which putspressure on the new substitute segment to setà a competitive price standard. While profit margins mayprove higher on a higher-priced item, theà productââ¬â¢s sensitivity to reputation for being a supposedlyââ¬Å"better, cheaper alternativeâ⬠to currently available options, which would satisfy the currently largely-unfulfilled demand for blood transfusion, would pressure Biopure to price its Oxyglobin according tocustomer expectations (See ââ¬Å"Existing optionsâ⬠, page 5 of this report). Those expectations, asà we can seefrom the attached appendix (Appendix 1 A and B), are that the price to the consumer be about $200 ($100to the veterinarian ââ¬â keeping theà 50% markup), which would give the company the largestà marginal gainin revenues (higher prices are actually marginalà losses! ), while still retaining the major demand (weconsider emergency care centers more important here,à since they have, proportionally, a much largerdemand than primary care centers). In terms of theà price difference between Oxyglobin and its competitorin the human segment, Baxter, the latter spent $50 million more on RD than Biopure, so the pricepremium on Baxter can beà justified by higher costs; in addition, Biopureââ¬â¢s per-unit costs are significantlysmaller because it uses cattle blood. In addition, Biopure may price Hemopure slightly higher because ofà the extra processing that goes into making it,à as well as the variation inà the segment and target audience(people are willing to spend more onà themselves than on animals). Distribution. Biopure should only target emergency careà practices. Although those only make up 5% ofà the overall industry, 75% primary care specialists will referà an acute blood loss case (such as a trauma)à toone of these centers. Furthermore, Biopure should target large practices (3+ doctors) through regionaldistributors, both of which account for the largest sales inà the industry. Considering the limited volume ofà supplies Biopure is going to have, aà national distribution may not be desirable right away, until thecompany at least increases its production capabilities. A regional distributor would be local enough tounderstand the specific needs of its market (e. g. , New England), and a larger vet practice could provemore efficient (and less costly) inà terms of the availability of materials andà the reduction of transfers,thereby also reducing the consumerââ¬â¢s costs and increasing the rateà of success by providing a quickerà service (in other words, it would have moreà cases, but more doctors available toà help overall, fewercases per doctor ââ¬â see Exhibit 7). Of course, the drawback is that a large clinic would not be as personal. The 1 million dollar question: Should Oxyglobin be launched? ââ¬â Yes. â⬠¢Launching early allows for an audience test:? Achieve acclaim/recognition for a break-through discovery that is beneficial because it-Fulfills an unsatisfied/dissatisfied need (better quality bloodà transfusion, availability);-Reduces costs to both suppliers and consumers.? Easier entry into secondary (human) market ââ¬âà ââ¬Å"tested on animalsâ⬠ââ¬â more trustedà than untestedcompetitors.? Potential to utilize production to full potential (instead of splitting up with Hemopure); later on, dividebased on larger per-unit profit (andà not necessarily the stated 150:300 ratio).? If fails or doesnââ¬â¢t test well: ââ¬â Would aid in the decision about improving current human version (complete discontinuation notan option due toà the immense initial investment in RD);- Reduce the shock of having to change both formulas (processes) simultaneously ââ¬â longer timespan gives better flexibility and more time for testing and improvement ââ¬â less drastic. Hemopure and Oxyglobin,à although similar in purposes, are meant for two completelydifferent segments; they should not be compared based on price because price expectations aredifferent for humans than they areà for animal needs; the demand for Oxyglobinà is clear andsignificant, while the demand for the same product in the human market is questionable. Therefore, stick with Oxyglobin ââ¬â which alrea dy has the approval ââ¬â and launch it. How to cite Blood Transfusion, Essay examples
Blood Transfusion Free Essays
BIOPURE INDUSTRIESA Marketing Analysis Based on the data from the case study by Jonn Gourville, Biopure Corporation , HBS, 1998April 20, 2005By Veronica Stepanova Executiveà Summaryâ⬠¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦ 2 Situation AnalysisI. Humanà Marketâ⬠¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦.. We will write a custom essay sample on Blood Transfusion or any similar topic only for you Order Now 3II. Animalà Marketâ⬠¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦.. 5 Marketing Planà for oxyglobinâ⬠¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦. 6 Finalà decisionâ⬠¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦Ã¢â¬ ¦ 7 Appendix 1 A (Excel documents, separate attachment) Appendix 1 B Executive Summary Many opportunities are available in the human blood market due to several disadvantages of thecurrently available alternatives. Even more opportunities exist in theà animal blood market. â⬠¢Oxyglobin should be positioned as a high-quality product designed for middle- to upper-classbudgets. â⬠¢The price for Oxyglobin should be about $200 for the consumer and around $100 for the supplier(animal hospital) to account for distribution markups and otherà carrying costs. â⬠¢Distribution should be oriented in the regionalà vicinity of the operation and implement largerclinics. In addition, only emergency clinics are to be targeted. Current opportunities are favorable for Oxyglobinââ¬â¢s launch. Situation Analysis I. Human blood market. â⬠¢Patients with acute blood loss fromà traumaà and surgery ââ¬â 40% individuals aged 65+. â⬠¢Chronic anemiaà patients (any age) ââ¬â 1. 5 million for the year 1995. â⬠¢Blood loss, resulting from trauma (e. g. car accident) and exceeding 2-3 units (1 unit = 10% ofà total blood content of human body) needs immediateà blood transfusion. â⬠¢Price is largely cost-based (storage, implementation) ââ¬â blood donation is free. Existing options. â⬠¢Redà blood cellsà and their components (hemoglobin, platelets, and plasma) areà collected viadonations, organized by blood collection centers andà then transfused into patients. â⬠¢Current options allow for storage for 6à weeks in refrigerated conditions, consequently disposed ofà if unused. Hemoglobin uses oxygen-carrying efficiency by 50% if not usedà within the first few weeks. â⬠¢Blood transfusion is subject to blood typing (A, B,à AB, O, positive, negative) andreception/rejection by the body. Incorrect matching may be fatalà for the patient. Infection risks slow down the process ofà testing blood prior to its use and areà greater if blood isnot separated into components. Infections include the risks of AIDS, hepatitis B,à and contamination. â⬠¢Blood transfusion is available on-site only (hospital or emergency room); as aà result, 30% traumapatients die prior to operation. â⬠¢Blood supply is lower than demand, esp ecially during peak periods (summerà months and winterholidays, during which car and other travel increases ? fewer donors and more patients). Blood substitutes. â⬠¢3 companies in final stages awaiting FDAà approval (clinical testing). Entrance into market is difficult (all current processes patented) andà time-consuming ââ¬â may takeup to 17 years (See case Exhibit 3). Potential to replace current blood drawing process byà component separation and purification, aswell as chemical modification and stabilization of hemoglobin. Reduced risk of contamination and increased storage capability of 2 years. Added benefits for patients with constricted or restricted blood vessels (smaller size improvedaccessibility to organs). Possibility of adapting animal blood cells for use inà humans. Risk of toxicity and body rejection (sped upà excretion). Competitors/industry players .A. Baxter à Northfield Laboratories. â⬠¢Both rely on human blood supply toà derive hemoglo bin. â⬠¢Red blood cells obtained from expired banks. â⬠¢Require refrigeration. Baxter: â⬠¢Leader in development and manufacturing of blood-oriented medical equipment. â⬠¢Large facility ââ¬â production capacity of 1 million units/year, spent $250à million on RD. â⬠¢Product ââ¬â HemAssist ââ¬â to beà priced between $600-$800. Northfield: â⬠¢Small facility ââ¬âà 10,000-unit production capability but possible expansion intoà 300,000 units/year. Focus on single product (PolyHeme), $70 million spent on development. B. Biopure Corporation. â⬠¢Specializes in protein purification for pharmaceutical use. â⬠¢Hemopure 2 years away from final approval. â⬠¢Derived from the blood of cattle. â⬠¢Production capacity of 150,000 butà possible production limitations due to expected concurrentusage of production equipment for animal version. â⬠¢Need for removal ofà hemoglobin clusters from product? excess process inà production abi lity. â⬠¢Cost for Biopure at $1. 50 per unit of animal blood, but plan to match Baxterââ¬â¢s price for finalconsumer product. II. Animal blood market. â⬠¢Mainly cats (35%) and dogs (50%). â⬠¢800 dogs were brought to emergencyà treatment due to acute blood loss in 1995,à 2. 5% severe. Existing options. â⬠¢15,000 veterinary clinics. â⬠¢5% of vet clinics perform emergency care, with a 75% referral rate from primary careà clinics. â⬠¢Current blood banks insufficient, demand greatly exceeds supply: 2. 5 out of 30à cases treated. â⬠¢93% blood drawn from donor animals (78%à in emergencies) ââ¬â an ethically questionable practice. â⬠¢150 units of blood transfused per emergency care, 17 perà primary care center (Appendix A). No effective blood typing or cross-matching systems. â⬠¢Blood collection, storage, and transfusion too costly for proper operation. â⬠¢Current cost of clinical careà to animal owners relatively high, undesirable. ? 84% doctor dissatisfaction with current alternatives. Blood substitutes. â⬠¢Biopureââ¬â¢s Oxyglobin currently the only exi stingà FDA-approved substitute ready for launch. â⬠¢No evident chemical difference in theà production process between animal and human supplement. â⬠¢Animal supplement approved sooner than human equivalent due to less-strict regulations in theanimal consumer market. Production capacity of 300,000 units, $200 million spent on development (combined withHemopure) Marketing Plan for OxyglobinPositioning strategy. Most animal owners (enthusiasts) can beà assumed to be within the middle toà upperincome class, based on the extraneous costs of owning an animal (refer to case Exhibit 8 for a summary ofà average costs of keeping aà pet). However, many consumers proved to beà price-conscious about spendingadditional funds on optional services (this will be analyzed further in theà pricing strategy); therefore, nopremium strategy should be used. The product should be positioned asà a high-quality supplement forblood transfusion, available to (affordable by) most animal owners. Pricing strategy. As cited, animalà owners expect to spend limited amounts of money onà animal care; thisis slightly different for emergency situations, where customers are willing to spend more,à as demonstratedby the survey results (Exhibit 8; Table B). The typical cost of aà blood transfusion to the customer iscurrently $100 for the traditional method; however, this price wasà said to have been cost-unjustified. Still,veterinarians were cited as theà trusted source for determining a patientââ¬â¢s treatment selection, which putspressure on the new substitute segment to setà a competitive price standard. While profit margins mayprove higher on a higher-priced item, theà productââ¬â¢s sensitivity to reputation for being a supposedlyââ¬Å"better, cheaper alternativeâ⬠to currently available options, which would satisfy the currently largely-unfulfilled demand for blood transfusion, would pressure Biopure to price its Oxyglobin according tocustomer expectations (See ââ¬Å"Existing optionsâ⬠, page 5 of this report). Those expectations, asà we can seefrom the attached appendix (Appendix 1 A and B), are that the price to the consumer be about $200 ($100to the veterinarian ââ¬â keeping theà 50% markup), which would give the company the largestà marginal gainin revenues (higher prices are actually marginalà losses! ), while still retaining the major demand (weconsider emergency care centers more important here,à since they have, proportionally, a much largerdemand than primary care centers). In terms of theà price difference between Oxyglobin and its competitorin the human segment, Baxter, the latter spent $50 million more on RD than Biopure, so the pricepremium on Baxter can beà justified by higher costs; in addition, Biopureââ¬â¢s per-unit costs are significantlysmaller because it uses cattle blood. In addition, Biopure may price Hemopure slightly higher because ofà the extra processing that goes into making it,à as well as the variation inà the segment and target audience(people are willing to spend more onà themselves than on animals). Distribution. Biopure should only target emergency careà practices. Although those only make up 5% ofà the overall industry, 75% primary care specialists will referà an acute blood loss case (such as a trauma)à toone of these centers. Furthermore, Biopure should target large practices (3+ doctors) through regionaldistributors, both of which account for the largest sales inà the industry. Considering the limited volume ofà supplies Biopure is going to have, aà national distribution may not be desirable right away, until thecompany at least increases its production capabilities. A regional distributor would be local enough tounderstand the specific needs of its market (e. g. , New England), and a larger vet practice could provemore efficient (and less costly) inà terms of the availability of materials andà the reduction of transfers,thereby also reducing the consumerââ¬â¢s costs and increasing the rateà of success by providing a quickerà service (in other words, it would have moreà cases, but more doctors available toà help overall, fewercases per doctor ââ¬â see Exhibit 7). Of course, the drawback is that a large clinic would not be as personal. The 1 million dollar question: Should Oxyglobin be launched? ââ¬â Yes. â⬠¢Launching early allows for an audience test:? Achieve acclaim/recognition for a break-through discovery that is beneficial because it-Fulfills an unsatisfied/dissatisfied need (better quality bloodà transfusion, availability);-Reduces costs to both suppliers and consumers.? Easier entry into secondary (human) market ââ¬âà ââ¬Å"tested on animalsâ⬠ââ¬â more trustedà than untestedcompetitors.? Potential to utilize production to full potential (instead of splitting up with Hemopure); later on, dividebased on larger per-unit profit (andà not necessarily the stated 150:300 ratio).? If fails or doesnââ¬â¢t test well: ââ¬â Would aid in the decision about improving current human version (complete discontinuation notan option due toà the immense initial investment in RD);- Reduce the shock of having to change both formulas (processes) simultaneously ââ¬â longer timespan gives better flexibility and more time for testing and improvement ââ¬â less drastic. Hemopure and Oxyglobin,à although similar in purposes, are meant for two completelydifferent segments; they should not be compared based on price because price expectations aredifferent for humans than they areà for animal needs; the demand for Oxyglobinà is clear andsignificant, while the demand for the same product in the human market is questionable. Therefore, stick with Oxyglobin ââ¬â which alrea dy has the approval ââ¬â and launch it. How to cite Blood Transfusion, Essay examples
Tuesday, May 5, 2020
Cleopatra A Hellenistic Ruler of Egypt free essay sample
She is undoubtedly one of the most famous persons of her time and there is a huge amount of evidence to support how she has shaped the Ancient world. In her lifetime Cleopatra was able to achieve a lot more then what was expected of her as she was a female ruler in a time when men dominated and shaped the Ancient world as ruler of Egypt. Cleopatra had a heavy influence on the Roman Empire and played a crucial part in the power struggle of the Octavianââ¬â¢s. However Cleopatraââ¬â¢s significants extends beyond the grave, she was able to achieve what she had always wanted: to keep her legend alive and form a symbol of female sexuality and power. In her lifetime Cleopatra was able to accomplish many great things as ruler of Egypt . As she was a female ruler she was not well accepted by most as she lived in a period where men where superior to females. We will write a custom essay sample on Cleopatra: A Hellenistic Ruler of Egypt or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page At the time Cleopatra was ruling there was a growing interest in the Egyptian empire as both Roman and Egyptian forces where fighting for its ownership. Cleopatra was able to keep the political structure of the empire together and ensured the Ptolemaic dynasty continued, however her death lead to the downfall of the Egyptian Empire as the Roman rule of Caesar Augustusââ¬â¢s began. Cleopatra was significant to the Ancient world as she was able to use her sexuality, persuasiveness and seductive abilities to influence her reign and impact as Queen of Egypt. This can be seen through her relationships with Julius Caesar and Mark Antony two of the most influential figures in the Roman Empire at the time. According to the Historian Cassius Dio, Caesar ââ¬Å"was spellbound the moment he set eyes on herâ⬠(Cassius D, 1986 p35). It has been recorded by many historians that Cleopatra was incredibly beautiful. Archaeological evidence found in Thebes of toilet boxes and other various make up products suggest that Cosmetics were basically invented by Egyptians. Cleopatra used these products to enhance her beauty and appearance which would have made her more attractive then most Roman females. It was through her relationships with Caesar and Mark Antony and surpassable beauty that Cleopatra was able to gain power as ruler, effectively increasing her significance to a study of the Ancient World.
Wednesday, April 1, 2020
A Comparison Contrast Of A Brave New World And 1984 Essays
A Comparison Contrast of A Brave New World and 1984 Although many similarities exist between Aldous Huxley's A Brave New World and George Orwell's 1984, the works books though they deal with similar topics, are more dissimilar than alike. A Brave New World is a novel about the struggle of Bernard Marx, who rejects the tenants of his society when he discovers that he is not truly happy. 1984 is the story of Winston who finds forbidden love within the hypocrisy of his society. In both cases, the main character is in quiet rebellion against his government which is eventually found to be in vain. Huxley wrote A Brave New World in the third person so that the reader could be allotted a more comprehensive view of the activities he presents. His characters are shallow and cartoon-like (Astrachan) in order to better reflect the society in which they are entrapped. In this society traditional notions of love and what ideally should come out of it have long been disregarded and are now despised, "Mother, monogamy, romance. High spurts the fountain; fierce and foamy the wild jet. The urge has but a single outlet." (Huxley 41) The comparison to a wild jet is intended to demonstrate the inherent dangers in these activities. Many of the Brave New World's social norms are intended to 'save' its citizens from anything unpleasant through depriving them of the opportunity to miss anything overly pleasant. The society values, ACOMMUNITY, IDENTITY, STABILITY," (Huxley 1) supersede all else in a collective effort. Soma, the magical ultimate drug is what keeps the population from revolting. "What you need is a gramme of soma... All the advantages of Christianity and alcohol; none of their defects." The drug is at the forefront of their daily lives providing freedom from life's every ill. "The word comes from the Sanskrit language of ancient India. It means both an intoxicating drink used in the old Vedic religious rituals there and the plant from whose juice the drink was made- a plant whose true identity we don't know." (Astrachan) The drug is used as a form of recreation, like sex, and its use is encouraged at any opportunity, especially when great emotions begin to arise. They are conditioned to accept this to calm and pacify them should they begin to feel anything too intensely. The conditioning also provides them with their place and prevents them from participating in social activities which they needn't take part in. (Smith) Class consciousness which Americans are so reluctant to acknowledge is taught through hypnop?dia (the repetition of phrases during sleep akin to post hypnotic suggestion) for all social classes: These names are letters in the Greek alphabet, familiar to Huxley's original English readers because in English schools they are used as grades- like our As, Bs, etc.- with Alpha plus the best and Epsilon minus the worst. In Brave New World, each names a class or caste. Alphas and Betas remain individuals; only Gammas, Deltas, and Epsilons are bokanovskified. (Astrachan) The conditioning is begun at an extremely young age and is by modern real-world standards cruel, AThe screaming of the babies suddenly changed its tone. There was something desperate, almost insane, about the sharp spasmodic yelps to which they now gave utterance." (Huxley 20) The children's "Pavlovian" conditioning with electric shocks is later compared to the wax seals which used to grace the seams of letters (Astrachan), "Not so much like drops of water, though water, it is true, can wear holes in the hardest granite; rather, drops of liquid sealing-wax, drops that adhere, incrust, incorporate themselves with what they fall on, till finally the rock is all one scarlet blob." The entire society is conditioned to shrink away from intense emotion, engage in casual sex, and take their pacifying Soma. In 1984, a first-person book partly narrated by the main character's internal dialogue, the great party leader is "Big Brother," a fictional character who is somewhat more imposing than "Ford," of Huxley's book, named after the industrialist Henry Ford (Astrachan). The main character Winston fears Big Brother and is much more aware of his situation than any of the characters in A Brave New World who are constantly pacified by soma. In A Brave New World
Saturday, March 7, 2020
Questions for a College Representative
Questions for a College Representative Are you wondering how you could start a conversation with a college representative? Here are some tips thatll help you have a productive conversation with your college representative. Lets get answers to your important questions. College Fair Topics and Questions Ideas First, its a good idea to write out a list of things that are important to you before you go. You shouldnt feel like you have strange priorities or weird questions. Maybe something off-beat is interesting to you. College representatives hear the same questions all the time, so theyll be glad to hear something new. If you wonder about LGBTQIA life on campus, the potential for racial tension, or if youre worried about spiders in the dorms, go ahead and ask about it. Start with Hello, how are you? or Hi, my name is ... for a relaxed beginning to your conversation.Try not to ask a vague question like Tell me about your college, since the representative will have no idea where to start. That can be frustrating for the college representative and the student because the conversation will have no direction.Be specific with questions by saying things like Tell me about class spirit or Can you give me examples of some campus traditions? instead. Questions phrased in such a way will give you a sense of the atmosphere and give the representative something specific to talk about.Ask for a list of majors that you could take with you. You could look over it later.Ask about the enrollment deadline and the recommendations for taking the SAT. Some colleges will need your scores earlier for admission considerations.Ask if subject scores (like SAT II Math or History) are required or recommended.Feel free to ask if the representative can waive your application fee , but know that this usually works best at private colleges. Ask if there are any scholarship secrets. There are many little-known tricks that differ from college to college, but the conversation doesnt always get around to this in a rushed environment like a college fair.You will want to know the admission requirements, of course. You may also want to ask whether admissions officers make decisions on numbers, or if they consider activities. Some collegesà go by scores and grades and follow a formula. Other colleges give greater weight to activities, experience, and interests.Ask if a student leader can contact you to give you a students perspective. If its possible, provide the representative an email address for this.Go ahead and ask about the food. Sometimes there are many choices, and other times there arent. Remember, youll have to live with it for four years.Ask how the food plan works.Find out the safety history of the campus and the surrounding town. Sometimes the campus rests in an area where theres a high crime rate just outside th e area considered the campus. A representative may not mention this. This is also something you should research on your own before you get too attached to the dream. Be safe! Ask how many of the students drop out, transfer away, or how many stay and graduate. College representatives may cringe at this one because student retention is a touchy issue at many colleges. A low retention rate may be a warning sign, though.Ask: Whats the biggest complaint from current students?Is tutoring available?If class size is important, ask about it. Keep in mind, however, that class sizes are less important when good individual tutoring is available.Find out if tutoring is free.Ask for a direct phone number for an admission counselor and a financial aid counselor to avoid getting caught up in an automated phone quagmire at some point. Smaller colleges will be happy to provide this, but larger colleges may not. Its always worth a try though.Find out if the administration listens to student concerns. This is one of the things you might want to ask a student leader.Ask if youll have to pay for parking or if youll have to walk a million miles from a parking lot to your classe s. If you are very conservative or very liberal in your thinking, ask about the political and social climate. This is one of the things that could cause a feeling of discomfort or alienation down the road, so its not a silly question.
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